Kepler Host Agnostic Microbiome Profiler

Good news! We are pleased to announce Kepler, our latest profiling algorithm that sets the standard in accuracy by seamlessly integrating the sensitivity of K-mer based taxonomic classification with the precision of read alignment based abundance estimation. To learn more about Kepler and its benchmarking, please download the Kepler Benchmarking whitepaper .

What does this mean for you? Here are some frequently asked questions:

  1. I have samples I ran previously on CosmosID-HUB and I would like to rerun them with Kepler, how do I do that?
    Please contact [email protected] for more information on how to re-profile your existing data on CosmosID-HUB with Kepler.

  2. For upcoming/future Bioinformatics services project delivery, will I automatically get taxonomic profiling results through Kepler?
    Yes, the Bioinformatics services team will deliver your data on Kepler going forward. If you would like your old data re-profiled using Kepler, please contact [email protected].

  3. Will my Kepler profiling results differ from the current taxa workflow results?
    Yes, some differences are expected due to updates of the algorithm, database and taxonomy.

  4. Will Kepler provide taxonomic profiling data with GTDB taxonomy?
    Yes, Kepler uses GTDB taxonomy for providing lineage information on identified Bacteria and Archaea. To learn more about the differences between GTDB taxonomy and NCBI taxonomy for Bacteria and Archaea, please visit GTDB and NCBI taxonomy comparison