MaAsLin3 for Differential Abundance
Longitudinal and Complex Association Testing with MaAsLin3
You can also utilize the optional Longitudinal and Complex Association Formula to incorporate advanced metadata groupings, such as:
- Group Effects (such as participant_id for longitudinal studies)
- **Ordered Effects **(to cross-compare categorical variables with a natural ordering such as cancer stage, consumption frequency, or dosage group)
- Strata Effects (a single grouping variable to be included in matched case-control studies)